Jorge da Rocha, Houcemeddine Othman, Gerrit Botha, David Twesigomwe, Samah Ahmed, Laura Cottino, Britt Drögemolller, Faisal Fadlelmola, Philip Machanick, Mamana Mbiyavanga, others .
The extent and impact of variation in ADME genes in sub-Saharan African populations .
bioRxiv ,
2020.
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Wan-Chun Chang, Riichiro Abe, Paul Anderson, Wanpen Anderson, Michael R Ardern-Jones, Thomas M Beachkofsky, Teresa Bellón, Agnieszka K Biala, Charles Bouchard, Gianpiero L Cavalleri, others .
SJS/TEN 2019: From science to translation .
Journal of dermatological science ,
2020.
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Galen EB Wright, Nicholas S Caron, Bernard Ng, Lorenzo Casal, William Casazza, Xiaohong Xu, Jolene Ooi, Mahmoud A Pouladi, Sara Mostafavi, Colin JD Ross, others .
Gene expression profiles complement the analysis of genomic modifiers of the clinical onset of Huntington disease .
Human molecular genetics ,
2020.
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Hailey Findlay Black, Galen EB Wright, Jennifer A Collins, Nicholas Caron, Chris Kay, Qingwen Xia, Larissa Arning, Emilia K Bijlsma, Ferdinando Squitieri, Huu Phuc Nguyen, others .
Frequency of the loss of CAA interruption in the HTT CAG tract and implications for Huntington disease in the reduced penetrance range .
Genetics in Medicine ,
2020.
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Britt I Drögemöller, Galen EB Wright, Cody Lo, Tan Le, Beth Brooks, Amit P Bhavsar, Shahrad R Rassekh, Colin JD Ross, Bruce C Carleton .
Pharmacogenomics of Cisplatin-Induced Ototoxicity: Successes, Shortcomings and Future Avenues of Research .
Clinical Pharmacology & Therapeutics ,
2019.
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Zulfan Zazuli, Leila S Otten, Britt I Drögemöller, Mara Medeiros, Jose G Monzon, Galen EB Wright, Christian K Kollmannsberger, Philippe L Bedard, Zhuo Chen, Karen A Gelmon, others .
Outcome Definition Influences the Relationship Between Genetic Polymorphisms of ERCC1, ERCC2, SLC22A2 and Cisplatin Nephrotoxicity in Adult Testicular Cancer Patients .
Genes ,
2019.
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Galen EB Wright, Jennifer A Collins, Chris Kay, Cassandra McDonald, Egor Dolzhenko, Qingwen Xia, Kristina Bečanović, Britt I Drögemöller, Alicia Semaka, Charlotte M Nguyen, others .
Length of uninterrupted CAG, independent of polyglutamine size, results in increased somatic instability, hastening onset of Huntington disease .
The American Journal of Human Genetics ,
2019.
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Galen EB Wright , Jennifer A. Collins, Chris Kay, Cassandra McDonald, Egor Dolzhenko, Qingwen Xia, Kristina Bečanović, Alicia Semaka, Charlotte M. Nguyen, Brett Trost, Fiona Richards, Emilia K. Bijlsma, Ferdinando Squitieri, Stephen W. Scherer, Michael A. Eberle, Ryan K.C. Yuen, Michael R. Hayden .
Length of uninterrupted CAG repeats, independent of polyglutamine size, results in increased somatic instability and hastened age of onset in Huntington disease .
bioRxiv ,
2019.
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DOI
André BP van Kuilenburg, Maja Tarailo-Graovac, Phillip A Richmond, Britt I Drögemöller, Mahmoud A Pouladi, René Leen, Koroboshka Brand-Arzamendi, Doreen Dobritzsch, Egor Dolzhenko, Michael A Eberle, others .
Glutaminase Deficiency Caused by Short Tandem Repeat Expansion in GLS .
New England Journal of Medicine ,
2019.
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Galen E.B. Wright, Nicholas S. Caron, Bernard Ng, Lorenzo Casal, Xiaohong Xu, Jolene Ooi, Mahmoud A Pouladi, Sara Mostafavi, Colin J.D. Ross, Michael R. Hayden .
Gene expression profiles complement the analysis of genomic modifiers of the clinical onset of Huntington disease .
bioRxiv ,
2019.
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DOI
Chris Kay, Jennifer A Collins, Galen EB Wright , Fiona Baine, Zosia Miedzybrodzka, Folefac Aminkeng, Alicia J Semaka, Cassandra McDonald, Mark Davidson, Steven J Madore, others .
The molecular epidemiology of Huntington disease is related to intermediate allele frequency and haplotype in the general population .
American Journal of Medical Genetics Part B: Neuropsychiatric Genetics ,
2018.
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Mark McCormack, Hongsheng Gui, Andrés Ingason, Doug Speed, Galen EB Wright , Eunice J Zhang, Rodrigo Secolin, Clarissa Yasuda, Maxwell Kwok, Stefan Wolking, others .
Genetic variation in CFH predicts phenytoin-induced maculopapular exanthema in European-descent patients .
Neurology ,
2018.
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Britt I Drögemöller, Beth Brooks, Jose G Monzon, Galen EB Wright , Geoffrey Liu, Daniel J Renouf, Christian Kollmannsberger, Phillipe L Bedard, Michael R Hayden, Karen A Gelmon, others .
Further investigation of the role of ACYP2 and WFS1 pharmacogenomic variants in the development of cisplatin-induced ototoxicity in testicular cancer patients .
Clinical Cancer Research ,
2018.
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Kaarina Kowalec*, Galen EB Wright *, Britt I Drögemöller, Folefac Aminkeng, Amit P Bhavsar, Elaine Kingwell, Eric M Yoshida, Anthony Traboulsee, Ruth Ann Marrie, Marcelo Kremenchutzky, others, *Authors contributed equally to this work .
Common variation near IRF6 is associated with IFN-beta-induced liver injury in multiple sclerosis .
Nature Genetics ,
2018.
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Britt I Drögemöller*, Galen EB Wright *, Joanne Shih, Jose G Monzon, Karen A Gelmon, Colin JD Ross, Ursula Amstutz, Bruce C Carleton, others, *Authors contributed equally to this work .
CYP2D6 as a treatment decision aid for ER-positive non-metastatic breast cancer patients: a systematic review with accompanying clinical practice guidelines .
Breast Cancer Research and Treatment ,
2018.
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DOI
Reo Tanoshima, Amna Khan, Agnieszka K Biala, Jessica N Trueman, Britt I Drögemöller, Galen EB Wright , Jafar S Hasbullah, Gabriella SS Groeneweg, Colin JD Ross, Bruce C Carleton, others .
Analyses of Adverse Drug Reactions - Nationwide Active Surveillance Network: Canadian Pharmacogenomics Network for Drug Safety Database .
The Journal of Clinical Pharmacology ,
2018.
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Chris Kay, Indira Tirado-Hurtado, Mario Cornejo-Olivas, Jennifer A Collins, Galen Wright , Miguel Inca-Martinez, Diego Veliz-Otani, Maria E Ketelaar, Ramy A Slama, Colin J Ross, others .
The targetable A1 Huntington disease haplotype has distinct Amerindian and European origins in Latin America .
European Journal of Human Genetics ,
2017.
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Britt I Drögemöller, Jose G Monzon, Amit P Bhavsar, Adrienne E Borrie, Beth Brooks, Galen EB Wright , Geoffrey Liu, Daniel J Renouf, Christian K Kollmannsberger, Philippe L Bedard, others .
Association between SLC16A5 genetic variation and cisplatin-induced ototoxic effects in adult patients with testicular cancer .
JAMA Oncology ,
2017.
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Britt I Drögemöller, Robin Emsley, Bonginkosi Chiliza, Lize van der Merwe, Galen EB Wright , Michelle Daya, Eileen Hoal, Anil K Malhotra, Todd Lencz, Delbert G Robinson, others .
The identification of novel genetic variants associated with antipsychotic treatment response outcomes in first-episode schizophrenia patients .
Pharmacogenetics and Genomics ,
2016.
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Zhe Wang, A Dessa Sadovnick, Anthony L Traboulsee, Jay P Ross, Cecily Q Bernales, Mary Encarnacion, Irene M Yee, Madonna de Lemos, Talitha Greenwood, Joshua D Lee, others .
Nuclear receptor NR1H3 in familial multiple sclerosis .
Neuron ,
2016.
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Zhe Wang, A Dessa Sadovnick, Anthony L Traboulsee, Jay P Ross, Cecily Q Bernales, Mary Encarnacion, Irene M Yee, Madonna de Lemos, Talitha Greenwood, Joshua D Lee, others .
Case-control studies are not familial studies .
Neuron ,
2016.
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Tyren M Dodgen, Warren E Hochfeld, Heidi Fickl, Sahle M Asfaha, Chrisna Durandt, Paul Rheeder, Britt I Drögemöller, Galen EB Wright , Louise Warnich, Christiaan DJ Labuschagne, others .
Introduction of the AmpliChip CYP450 Test to a South African cohort: a platform comparative prospective cohort study .
BMC Medical Genetics ,
2013.
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Britt Ingrid Drögemöller, Marieth Plummer, Lundi Korkie, Gloudi Agenbag, Anke Dunaiski, Dana Niehaus, Liezl Koen, Stefan Gebhardt, Nicol Schneider, Antonel Olckers, others .
Characterization of the genetic variation present in CYP3A4 in three South African populations .
Frontiers in Genetics ,
2013.
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Britt I Drögemöller, Galen EB Wright , Dana JH Niehaus, Liezl Koen, Stefanie Malan, Danielle M Da Silva, Renate Hillermann–Rebello, Anthony M La Grange, Mauritz Venter, Louise Warnich .
Characterization of the genetic profile of CYP2C19 in two South African populations .
Pharmacogenomics ,
2010.
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